Inferring a tumor progression model for neuroblastoma from genomic data.

@article{Bilke2005InferringAT,
  title={Inferring a tumor progression model for neuroblastoma from genomic data.},
  author={Sven Bilke and Qing-Rong Chen and Frank Westerman and Manfred Schwab and Daniel R. Catchpoole and Javed Khan},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2005},
  volume={23 29},
  pages={
          7322-31
        }
}
PURPOSE The knowledge of the key genomic events that are causal to cancer development and progression not only is invaluable for our understanding of cancer biology but also may have a direct clinical impact. The task of deciphering a model of tumor progression by requiring that it explains (or at least does not contradict) known clinical and molecular evidence can be very demanding, particularly for cancers with complex patterns of clinical and molecular evidence. MATERIALS AND METHODS We… CONTINUE READING
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