Inferring Gene Regulatory Networks by Singular Value Decomposition and Gravitation Field Algorithm

Abstract

Reconstruction of gene regulatory networks (GRNs) is of utmost interest and has become a challenge computational problem in system biology. However, every existing inference algorithm from gene expression profiles has its own advantages and disadvantages. In particular, the effectiveness and efficiency of every previous algorithm is not high enough. In this… (More)
DOI: 10.1371/journal.pone.0051141

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