Inferior mechanical properties of spastic muscle bundles due to hypertrophic but compromised extracellular matrix material.

@article{Lieber2003InferiorMP,
  title={Inferior mechanical properties of spastic muscle bundles due to hypertrophic but compromised extracellular matrix material.},
  author={Richard L. Lieber and Eva Runesson and Fredrik Einarsson and Jan Frid{\'e}n},
  journal={Muscle & nerve},
  year={2003},
  volume={28 4},
  pages={
          464-71
        }
}
The passive mechanical properties of small muscle fiber bundles obtained from surgical patients with spasticity (n = 9) and patients without neuromuscular disorders (n = 21) were measured in order to determine the relative influence of intracellular and extracellular components. For both types of patient, tangent modulus was significantly greater in bundles compared to identical tests performed on isolated single cells (P < 0.05). However, the relative difference between bundles and single… CONTINUE READING
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