Inference of expression-dependent negative selection based on polymorphism and divergence in the human genome.

@article{Osada2007InferenceOE,
  title={Inference of expression-dependent negative selection based on polymorphism and divergence in the human genome.},
  author={Naoki Osada},
  journal={Molecular biology and evolution},
  year={2007},
  volume={24 8},
  pages={1622-6}
}
  • Naoki Osada
  • Published 2007 in Molecular biology and evolution
There is a mounting evidence for the correlation between the gene expression pattern and sequence divergence. However, little is known about the relationship between the gene expression pattern and polymorphism. We compiled the gene expression, polymorphism, and divergence data from the public databases of the human genome. The ratios of nonsynonymous (A… CONTINUE READING