Infectious salmon anaemia virus (ISAV) isolates induce distinct gene expression responses in the Atlantic salmon (Salmo salar) macrophage/dendritic-like cell line TO, assessed using genomic techniques.

@article{Workenhe2009InfectiousSA,
  title={Infectious salmon anaemia virus (ISAV) isolates induce distinct gene expression responses in the Atlantic salmon (Salmo salar) macrophage/dendritic-like cell line TO, assessed using genomic techniques.},
  author={Samuel Tekeste Workenhe and Tiago S F Hori and Matthew L. Rise and Molly J. T. Kibenge and Frederick S B Kibenge},
  journal={Molecular immunology},
  year={2009},
  volume={46 15},
  pages={
          2955-74
        }
}
Infectious salmon anaemia virus (ISAV) is a marine orthomyxovirus of significant interest not only as a cause of a fatal disease of farmed Atlantic salmon resulting in severe economic losses to the aquaculture industry, but also as the only poikilothermic orthomyxovirus. ISAV targets vascular endothelial cells and macrophages, and is known to influence the expression of both innate and adaptive immune response relevant genes. ISAV isolates from different geographic regions have been shown to… CONTINUE READING
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