Infectious mononucleosis and mononucleosis syndromes.

  title={Infectious mononucleosis and mononucleosis syndromes.},
  author={Milan Fiala and Douglas C. Heiner and Judith Axler Turner and Barry Rosenbloom and Lucien B. Guze},
  journal={The Western journal of medicine},
  volume={126 6},
Infectious mononucleosis (IM) and cytomegalovirus (CMV) mononucleosis are caused by a primary infection with related viruses, Epstein-Barr virus (EBV) and CMV. Despite the similarity of clinical manifestations, basic differences exist: (1) The heterophil antibody (HA) response is absent in CMV mononucleosis, whereas it is present in IM. (2) In IM atypical lymphocytosis reflects proliferation of B cells early and of T cells later in the disease course; in CMV mononucleosis the situation appears… CONTINUE READING