Infectious hepatitis A virus particles produced in cell culture consist of three distinct types with different buoyant densities in CsCl.

Abstract

Although hepatitis A virus (HAV) released by infected BS-C-1 cells banded predominantly at 1.325 g/cm3 (major component) in CsCl, smaller proportions of infectious virions banded at 1.42 g/cm3 (dense HAV particles) and at 1.27 g/cm3 (previously unrecognized light HAV particles). cDNA-RNA hybridization confirmed the banding of viral RNA at each density, and… (More)

Topics

Cite this paper

@article{Lemon1985InfectiousHA, title={Infectious hepatitis A virus particles produced in cell culture consist of three distinct types with different buoyant densities in CsCl.}, author={Stanley M Lemon and Robin W Jansen and John E. Newbold}, journal={Journal of virology}, year={1985}, volume={54 1}, pages={78-85} }