Infectious diseases and immunity: special reference to major histocompatibility complex.

@article{Singh1997InfectiousDA,
  title={Infectious diseases and immunity: special reference to major histocompatibility complex.},
  author={Neeloo Singh and Shikha Agrawal and Anil K. Rastogi},
  journal={Emerging Infectious Diseases},
  year={1997},
  volume={3},
  pages={41 - 49}
}
Human leukocyte antigens (HLAs) are an inherent system of alloantigens, which are the products of genes of the major histocompatibility complex (MHC). These genes span a region of approximately 4 centimorgans on the short arm of human chromosome 6 at band p 21.3 and encode the HLA class I and class II antigens, which play a central role in cell-to-cell interaction in the immune system. These antigens interact with the antigen-specific cell surface receptors of T lymphocytes (TCR) thus causing… CONTINUE READING