Infectious diseases: Destroying Salmonella's camouflage

A new study in mice shows that the enzyme nicotinamide N-methyltransferase (Nnmt) is a key mediator of obesity and its metabolic complications (Nature 508, 258–262, 2014). Nnmt expression and activity is known to be upregulated in the fat tissue of obese humans and rodents. Barbara Kahn and her colleagues now find that knockdown of Nnmt expression in… CONTINUE READING