Infectious correlates of HIV-1 shedding in the female upper and lower genital tracts.

@article{Coleman2007InfectiousCO,
  title={Infectious correlates of HIV-1 shedding in the female upper and lower genital tracts.},
  author={Jenell Sheree Coleman and Jane E Hitti and Elizabeth Ann Bukusi and Christina W Mwachari and Angela Muliro and Rosemary Nguti and Reggie Gausman and Sarah Jensen and Dorothy Patton and David J Lockhart and Robert Coombs and Craig R Cohen},
  journal={AIDS},
  year={2007},
  volume={21 6},
  pages={755-9}
}
OBJECTIVES To determine the effects of vaginal, cervical, and endometrial infections on shedding of HIV-1 RNA in the female genital tract. DESIGN Cross-sectional. METHODS Antiretroviral-naive women from Nairobi, Kenya with CD4 cell counts >or= 350 cells/mul had plasma and endocervical wick samples collected for HIV quantification by real-time RNA reverse transcriptase-polymerase chain reaction. Vaginal and cervical Gram stains and endometrial biopsies were obtained. Vaginal Gram stain was… CONTINUE READING

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