Infectious complications of chronic lymphocytic leukemia.

  title={Infectious complications of chronic lymphocytic leukemia.},
  author={Punit D. Wadhwa and Vicki a. Morrison},
  journal={Seminars in oncology},
  volume={33 2},
Infectious complications continue to be one of the major causes of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL). The pathogenesis of infections in these patients is multifactorial. Hypogammaglobulinemia is an important predisposing factor for infection in patients with early-stage disease and for those treated with conventional alkylating agents. However, the proportion of patients treated with purine analogs and monoclonal antibodies such as rituximab and… CONTINUE READING


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