Infectious Tolerance Require IL-35 To Mediate Suppression and Cutting Edge: Human Regulatory T Cells

Abstract

Human regulatory T cells (T reg) are essential for the maintenance of immune tolerance. However, the mechanisms they use to mediate suppression remain controversial. Although IL-35 has been shown to play an important role in T reg-mediated suppression in mice, recent studies have questioned its relevance in human T reg. In this study, we show that human T… (More)

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