Infectious Diseases Society of America (IDSA) POSITION STATEMENT: Why IDSA Did Not Endorse the Surviving Sepsis Campaign Guidelines

  title={Infectious Diseases Society of America (IDSA) POSITION STATEMENT: Why IDSA Did Not Endorse the Surviving Sepsis Campaign Guidelines},
  author={Andre C. Kalil and David N. Gilbert and Dean L. Winslow and Henry Masur and Michael Klompas},
  journal={Clinical Infectious Diseases},
IDSA did not endorse the 2016 Surviving Sepsis Campaign Guidelines despite being represented in the working group that drafted the guidelines document. [] Key Result Leadership from the IDSA, the Surviving Sepsis Campaign Guidelines, and the Society of Critical Care Medicine had numerous amicable discussions primarily regarding the bolded, rated guidelines recommendations. Our societies had different perspectives, however, regarding the interpretation of the major studies that informed the guidelines…
The surviving sepsis controversy: a call to action for hospital medicine
It is time for hospitalists to weigh in on this important issue by formally commenting on the new guidelines, establishing research priorities, and leading future research studies in the field to help achieve consensus among all clinicians in the appropriate management of sepsis.
Evaluation and management of suspected sepsis and septic shock in adults
In this topic review, the management of sepsis and septic shock is discussed and definitions, diagnosis, pathophysiology, and investigational therapies for sepsi, as well as management ofsepsis in the asplenic patient are reviewed separately.
The Current and Future State of Pediatric Sepsis Definitions: An International Survey.
The 2005 consensus definitions were perceived to be the most useful for sepsis recognition, while Sepsis-3 definitions were stated as more useful for benchmarking, disease classification, enrollment into trials, and prognostication.
Impact of Sepsis Mandates on Sepsis Care: Unintended Consequences.
The risks and benefits of mandated care for sepsis are reviewed, with particular emphasis on the potential adverse consequences of common bundle components such as early empiric antibiotics, weight-based fluid administration, and serum lactate monitoring.
Empiric Antimicrobial Therapy in Critically Ill Septic Patients
Suggestions of empirical therapeutic regimens in sepsis/septic shock according to most likely pathogens in cause and sepsi source based on the recent recommendations of learned societies are made.
Incidence of Clostridium difficile Infection After Sepsis Protocol Antibiotics
It is found that CDI infections declined after implementation of a sepsis bundle, but there was, however, an increase in the number of patients being exposed to antibiotics after this hospital policy change.
Strategies for the Management of Sepsis.
T incidence of sepsis and mortality rates have remained consistent over the years despite advances in therapy, with mortality rates reported to be as high as 23.6% for patients diagnosed with septic
Quality of evidence supporting Surviving Sepsis Campaign Recommendations


Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016
Although a significant number of aspects of care have relatively weak support, evidence-based recommendations regarding the acute management of sepsis and septic shock are the foundation of improved outcomes for these critically ill patients with high mortality.
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
The task force concluded the term severe sepsis was redundant and updated definitions and clinical criteria should replace previous definitions, offer greater consistency for epidemiologic studies and clinical trials, and facilitate earlier recognition and more timely management of patients with sepsi or at risk of developing sepsic shock.
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference
This document reflects a process whereby a group of experts and opinion leaders revisited the 1992 sepsis guidelines and found that apart from expanding the list of signs and symptoms of sepsi to reflect clinical bedside experience, no evidence exists to support a change to the definitions.
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine.
Broad definitions of sepsis and the systemic inflammatory response syndrome were proposed, along with detailed physiologic parameters by which a patient may be categorized, and the use of severity scoring methods when dealing with septic patients was recommended as an adjunctive tool to assess mortality.
Monotherapy Is Adequate for Septic Shock Due to Gram-Negative Organisms.
Recommendations in favor of combination therapy can be traced to observational studies from the 1970s, 1980s, and 1990s that documented lower mortality rates in patients with Gram-negative bacteremia treated with two antibiotics rather than one, particularly among patients infected with Pseudomonas aeruginosa.
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. 1992.
An American College ofChest Physicians/Society ofCritical Care Medicine Consensus Conference was held in Northbrook in August 1991 with the goal of agreeing on a set of de6nitions that could be
Executive Summary: Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society.
  • A. Kalil, M. Metersky, J. Brożek
  • Medicine
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2016
These guidelines are intended for use by healthcare professionals who care for patients at risk for hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP), including specialists in infectious diseases, pulmonary diseases, critical care, and surgeons, anesthesiologists, hospitalists, and any clinicians and healthcare providers caring for hospitalized patients with nosocomial pneumonia.
The Impact of the Sepsis-3 Septic Shock Definition on Previously Defined Septic Shock Patients*
Although Sepsis-3 criteria identified a group of patients with increased organ failure and higher mortality, those patients who met the old criteria and not Sepsis -3 criteria still demonstrated significant organ Failure and 14% mortality rate.
Severe sepsis bundles
  • Parvez U Khan, J. Divatia
  • Medicine
    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine
  • 2010
Critical Care Units should develop management strategies to ensure compliance with the sepsis bundles in order to decrease hospital mortality due to severe sepsi.
Antibiotics for Sepsis: Does Each Hour Really Count, or Is It Incestuous Amplification?
  • M. Singer
  • Medicine
    American journal of respiratory and critical care medicine
  • 2017
A blind faith in the primacy of early antibiotics suits this purpose, yet I confess to being decidedly agnostic, and fearful.