Infections with human rhinovirus induce the formation of distinct functional membrane domains.

@article{Dreschers2007InfectionsWH,
  title={Infections with human rhinovirus induce the formation of distinct functional membrane domains.},
  author={Stephan Dreschers and Peter Franz and Claudia Dumitru and Barbara Wilker and Klaus Jahnke and Erich Gulbins},
  journal={Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology},
  year={2007},
  volume={20 1-4},
  pages={241-54}
}
The plasma membrane contains distinct domains that are characterized by a high concentration of sphingolipids and cholesterol. These membrane microdomains also referred to as rafts, seem to be intimately involved in transmembranous signaling and often initiate interactions of pathogens and the host cell membranes. Here, we investigated the further reorganization of membrane rafts in cultured epithelial cells and ex vivo isolated nasal cells after infection with rhinoviruses. We demonstrate the… CONTINUE READING