Infections in patients with immunodeficiency with thymoma (Good syndrome). Report of 5 cases and review of the literature.

@article{Tarr2001InfectionsIP,
  title={Infections in patients with immunodeficiency with thymoma (Good syndrome). Report of 5 cases and review of the literature.},
  author={Philip E. Tarr and Michael C Sneller and Leah Mechanic and Athena Economides and Christopher Eger and Warren Strober and Charlotte Cunningham-Rundles and Daniel R. Lucey},
  journal={Medicine},
  year={2001},
  volume={80 2},
  pages={123-33}
}
Immunodeficiency with thymoma (Good syndrome, GS) is a rare, adult-onset condition that is characterized by thymoma, hypogammaglobulinemia, and low numbers of peripheral B cells. CD4+ T lymphopenia and an inverted CD4:CD8+ T-cell ratio may be present. Here we report 5 patients with GS and infectious complications who were seen at 3 institutions between 1983 and 1999. Three patients had recurrent sinopulmonary infections, 3 had severe cytomegalovirus (CMV) disease, and 1 had Pneumocystis carinii… CONTINUE READING
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