Infections during tumour necrosis factor-alpha blocker therapy for rheumatic diseases in daily practice: a systematic retrospective study of 709 patients.

@article{Salliot2007InfectionsDT,
  title={Infections during tumour necrosis factor-alpha blocker therapy for rheumatic diseases in daily practice: a systematic retrospective study of 709 patients.},
  author={Carine Salliot and Laure Gossec and Adeline Ruyssen-Witrand and Mathieu Luc and Muriel Duclos and Sandra Guignard and Maxime R Dougados},
  journal={Rheumatology},
  year={2007},
  volume={46 2},
  pages={
          327-34
        }
}
OBJECTIVE To evaluate the rate of infections in rheumatic patients treated with tumour necrosis factor (TNF)-alpha blockers in daily practice and to determine potential risk factors of infections. METHODS Systematic retrospective study was conducted in a tertiary-referral centre of all patients receiving at least one TNF-alpha blocker, between 1997 and December 2004. Serious infections were defined as life-threatening, requiring hospitalization or sequelae. The incidence of infections during… CONTINUE READING
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