Infection of primary human bronchial epithelial cells by Haemophilus influenzae: macropinocytosis as a mechanism of airway epithelial cell entry.

@article{Ketterer1999InfectionOP,
  title={Infection of primary human bronchial epithelial cells by Haemophilus influenzae: macropinocytosis as a mechanism of airway epithelial cell entry.},
  author={Margaret R. Ketterer and J. Q. Shao and Douglas B. Hornick and Brigitte Buscher and Venkata Bandi and Michael A. Apicella},
  journal={Infection and immunity},
  year={1999},
  volume={67 8},
  pages={4161-70}
}
Nontypeable Haemophilus influenzae is an exclusive human pathogen which infects the respiratory epithelium. We have initiated studies to explore the interaction of the nontypeable H. influenzae strain 2019 with primary human airway epithelial cells by electron and confocal microscopy. Primary human airway cell cultures were established as monolayers on glass collagen-coated coverslips or on semipermeable membranes at an air-fluid interface. Scanning electron microscopy indicated that bacteria… CONTINUE READING

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