Infection of monocyte-derived macrophages with human immunodeficiency virus type 1 (HIV-1). Monocyte-tropic and lymphocyte-tropic strains of HIV-1 show distinctive patterns of replication in a panel of cell types

@article{Collman1989InfectionOM,
  title={Infection of monocyte-derived macrophages with human immunodeficiency virus type 1 (HIV-1). Monocyte-tropic and lymphocyte-tropic strains of HIV-1 show distinctive patterns of replication in a panel of cell types},
  author={Ronald G. Collman and N F Hassan and Robert Walker and Barbara Godfrey and Joann R Cutilli and J C Hastings and Henry Friedman and Steven D. Douglas and Noel Nathanson},
  journal={The Journal of Experimental Medicine},
  year={1989},
  volume={170},
  pages={1149 - 1163}
}
To characterize the host range of different strains of HIV-1, we have used four types of cells, primary monocyte-derived macrophages (MDM), primary PBL, a promonocyte cell line (U937), and a CD4+ T cell line (SUP-T1). These cells were infected with three prototype strains of HIV-1, a putative lymphocyte-tropic strain (IIIB), and two putative monocyte-tropic strains (SF162 and DV). Infections were monitored by assays for infectious virus, for cell-free and cell-associated viral antigen (p24… CONTINUE READING
59 Citations
12 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 59 extracted citations

References

Publications referenced by this paper.

Similar Papers

Loading similar papers…