Infection-induced inflammatory response of adipocytes in vitro

  title={Infection-induced inflammatory response of adipocytes in vitro},
  author={John J. M. Bouwman and Frank L. J. Visseren and K Paul Bouter and Rob J.A. Diepersloot},
  journal={International Journal of Obesity},
Background:Abdominal obesity plays an important role in the development of insulin resistance, diabetes mellitus and atherosclerosis. The exact pathophysiological mechanisms are unclear but adipocyte dysfunction is thought to be crucial. Infections are associated with the development of atherosclerosis as well as diabetes. In this study we investigated whether adipocytes can be infected and whether this results in production of inflammatory cytokines relevant for the development of… CONTINUE READING
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