Infection and rheumatoid arthritis: still an open question.

  title={Infection and rheumatoid arthritis: still an open question.},
  author={Carol A Hitchon and H S El-Gabalawy},
  journal={Current opinion in rheumatology},
  volume={23 4},
PURPOSE OF REVIEW This review focuses on recent research that explores the role of infectious organisms in the development of autoimmunity and rheumatoid arthritis (RA). RECENT FINDINGS Human and animal studies provide further evidence supporting a role for the periodontal pathogen, Porphyromonas gingivalis, in the development of RA. The microbiome plays a key role in the developing immune system. Alterations in the bowel microbiome lead to altered innate and adaptive immune responses… CONTINUE READING