Infection and childhood leukaemia near nuclear sites

@article{Kinlen1997InfectionAC,
  title={Infection and childhood leukaemia near nuclear sites},
  author={L. J. Kinlen},
  journal={The Lancet},
  year={1997},
  volume={349}
}
  • L. Kinlen
  • Published 7 June 1997
  • Biology
  • The Lancet
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To evaluate the possibility of increased cancer rates in communities around the Apollo-Parks nuclear facilities, a cancer incidence and a cancer mortality survey were conducted and no significant increases in the study counties for any cancer when comparisons were made with either the U.S. population or the control counties.
Perinatal exposure to infection and risk of childhood leukemia.
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An association between exposure to maternal lower genital tract infection in utero, and a subsequent risk for childhood leukemia, is documented, which indicates the importance of an early exposure.
Perinatal Risk Factors for Childhood Leukemia
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The present studies indicate that events during pregnancy or during the neonatal period are associated with increased risks of childhood and infant leukemia.

References

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The excess of childhood leukaemia near Sellafield: a commentary on the fourth COMARE report
TLDR
COMARE underestimates the special factors that would account, under the infection hypothesis, for the unusually large excess in Seascale, and pays insufficient attention to other communities near Sellafield which may have been affected by population mixing.
Cluster analysis and disease mapping—why, when, and how? A step by step guide
TLDR
Despite the fact that cluster analyses rarely prove fruitful in identifying causation, they may-like single case reports-have the potential to generate new knowledge and be used to address public concern about environmental hazards.
Childhood leukaemia and non-Hodgkin's lymphoma near large rural construction sites, with a comparison with Sellafield nuclear site
TLDR
The findings support the infection hypothesis and reinforce the view that the excess of childhood leukaemia and non-Hodgkin's lymphoma near Sellafield has a similar explanation.