Infection-Induced Anorexia: Active Host Defence Strategy

@article{Exton1997InfectionInducedAA,
  title={Infection-Induced Anorexia: Active Host Defence Strategy},
  author={Michael S. Exton},
  journal={Appetite},
  year={1997},
  volume={29},
  pages={369-383}
}
  • M. Exton
  • Published 1 December 1997
  • Biology, Medicine, Psychology
  • Appetite
In association with fever production, decreased food consumption is the most common sign of infection. This effect is often regarded as an undesirable manifestation of sickness. However, evidence suggests that just as many behaviours have now been shown to modify immunocompetence, infection-induced anorexia is a behaviour systematically organised for pathogen elimination. That is, anorexia is an active defence mechanism that is beneficial for host defence. This review details the mechanism of… 
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The neurobiology behind disease-avoidant ingestive behaviours is reviewed with special emphasis on the body energy balance (intake versus expenditure) and an evolutionary psychology perspective.
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