Infection, mimics, and autoimmune disease.

  title={Infection, mimics, and autoimmune disease.},
  author={Noel R. Rose},
  journal={The Journal of clinical investigation},
  volume={107 8},
  • Noel R. Rose
  • Published 2001 in The Journal of clinical investigation
observation that infection can precipitate an autoimmune disease dates back more than a century. The first human autoimmune disease described, paroxysmal cold hemoglobulinuria, was thought of as a late consequence of syphilis, and rheumatic fever is still associated with preceding streptococcal infection. In modern times, these associations have been attributed to molecular mimicry. In its simplest form, the concept of molecular mimicry states that antigenic determinants of infectious… CONTINUE READING


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Publications referenced by this paper.
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Dominant Tand B - cell epitopes in an autoantigen linked to Chagas ’ disease

N. Gironès
J . Clin . Invest . • 2001

Molecular mimicry and immune-mediated diseases.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology • 1998

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