Infected-host-cell repertoire and cellular response in the lung following inhalation of Francisella tularensis Schu S4, LVS, or U112.

@article{Hall2008InfectedhostcellRA,
  title={Infected-host-cell repertoire and cellular response in the lung following inhalation of Francisella tularensis Schu S4, LVS, or U112.},
  author={Joshua D Hall and Matthew D. Woolard and Bronwyn Gunn and Robin R. Craven and Sharon A. Taft-Benz and Jeffrey A Frelinger and Thomas H Kawula},
  journal={Infection and immunity},
  year={2008},
  volume={76 12},
  pages={5843-52}
}
Francisella tularensis causes systemic disease in humans and other mammals, with high morbidity and mortality associated with inhalation-acquired infection. F. tularensis is a facultative intracellular pathogen, but the scope and significance of cell types infected during disease is unknown. Using flow cytometry, we identified and quantified infected-cell types and assessed the impact of infection on cell populations following inhalation of F. tularensis strains U112, LVS, and Schu S4… CONTINUE READING

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