Infarct size and the protection of ischemic myocardium in pig, dog and human.

@article{Fujiwara1989InfarctSA,
  title={Infarct size and the protection of ischemic myocardium in pig, dog and human.},
  author={Hiroshi Fujiwara and Masako Matsuda and Yasuhiro Fujiwara and Masaki Ishida and Akio Kawamura and Genzou Takemura and Mitsugu Kida and Takashi Uegaito and Masashi Tanaka and Kazuya Horike},
  journal={Japanese circulation journal},
  year={1989},
  volume={53 9},
  pages={1092-7}
}
To define whether recanalization after occlusion can reduce the myocardial infarct size, we compared the infarct size in 25 pig hearts without collateral circulation, 35 dog hearts with collateral circulation and 11 human autopsied hearts with coronary thrombolysis at 2 to 6 hours after the onset of acute myocardial infarction. The data showed that % infarct size in the risk area increased according to the duration of occlusion. In the pig, % infarct size was 80 +/- 9% in the recanalization… CONTINUE READING

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