Infantile pyknocytosis: a cause of haemolytic anaemia of the newborn.

  title={Infantile pyknocytosis: a cause of haemolytic anaemia of the newborn.},
  author={St{\'e}phanie Eyssette-Guerreau and Brigitte Bader-Meunier and Lo{\"i}c Garçon and Corinne Guitton and Th{\'e}r{\`e}se Cynober},
  journal={British journal of haematology},
  volume={133 4},
This study defined the incidence, clinical and haematological characteristics of infantile pyknocytosis in a monocentric retrospective study of 149 blood samples referred for unexplained neonatal haemolytic anaemia. Pyknocytosis was diagnosed in 14 patients (9.4%). All patients had neonatal jaundice and severe anaemia (mean nadir haemoglobin: 6.8 g/dl) at a mean age of 21 d. The percentage of pyknocytes was 4-23%. Packed red blood cell transfusions were needed in 11 of 14 patients. Haemoglobin… CONTINUE READING