Inescapable shock induces the opposite changes of the plus-maze test behavior in rats with divergent coping strategy.

@article{Zhukov1994InescapableSI,
  title={Inescapable shock induces the opposite changes of the plus-maze test behavior in rats with divergent coping strategy.},
  author={Dmitry Zhukov and K P Vinogradova},
  journal={Physiology & behavior},
  year={1994},
  volume={56 5},
  pages={1075-9}
}
Behavior in the elevated plus-maze and plasma corticosterone levels were investigated in Koltushi high-avoidance (KHA) and low-avoidance (KLA) rat strains subjected to inescapable shock (IS) or daily handling for 10 days. These strains have been genetically selected on the basis of divergent acquisition of a conditioned avoidance response in a two-way shuttle-box. Naive KHA rats were more anxious than KLA ones. Following exposure to IS, the time spent in open arms was increased in KHA rats but… CONTINUE READING

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