Inescapable shock activates serotonergic neurons in all raphe nuclei of rat.

@article{Takase2004InescapableSA,
  title={Inescapable shock activates serotonergic neurons in all raphe nuclei of rat.},
  author={Luiz Fernando Takase and Maria In{\^e}s Nogueira and Michael V Baratta and Sondra T. Bland and Linda R. Watkins and Steven F. Maier and Casimir A. Fornal and Barry L. Jacobs},
  journal={Behavioural brain research},
  year={2004},
  volume={153 1},
  pages={233-9}
}
Animal studies examining the effects of stress upon brain serotonergic neurons have not presented a clearcut and consistent picture. One stressor that has been shown to exert a consistently strong effect on serotonin release and c-fos activation in the dorsal raphe nucleus of rats is a series of inescapable electrical shocks. Using immunohistochemical double labeling for c-fos activation and serotonin, we examined the effects of delivering 100 inescapable tailshocks to rats on serotonergic… CONTINUE READING