Industry watch: heat-not-burn tobacco products are about to reach their boiling point

@article{Caputi2016IndustryWH,
  title={Industry watch: heat-not-burn tobacco products are about to reach their boiling point},
  author={Theodore L. Caputi},
  journal={Tobacco Control},
  year={2016},
  volume={26},
  pages={609 - 610}
}
Heat-not-burn tobacco products (HNB), including Reynolds American's (RA) ‘Eclipse’ and ‘Revo’ and Philip Morris International's (PMI) ‘Heatbar’, are devices that heat tobacco to ∼500°F, producing an inhalable aerosol. Since 1988, tobacco companies have perennially introduced HNB and marketed them as healthier than conventional cigarettes. These claims, refuted by researchers,1 failed to lure consumers. Each reincarnation of HNB was commercially unsuccessful, and most HNB products were… 
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TLDR
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References

SHOWING 1-10 OF 21 REFERENCES
Heated Tobacco Products Create Side-Stream Emissions: Implications for
A number of tobacco manufacturers are promoting products where the tobacco is reportedly "heated" rather than burned. It has been claimed that certain heated tobacco products produce only mainstream
Awareness and use of electronic cigarettes and heat-not-burn tobacco products in Japan.
TLDR
Nearly half the respondents in a Japanese internet survey were aware of e-cigarettes and heat-not-burn tobacco products, 6.6% had ever used, with a relatively higher percentage among the younger population.
Reduced Exposure to Harmful and Potentially Harmful Smoke Constituents With the Tobacco Heating System 2.1
TLDR
Exposure markers to harmful and potentially harmful smoke constituents were lowered with the THS 2.1 and Notwithstanding possible use adaption through consumption or puffing behavior, the exposure to harmful smoke constituent was markedly reduced with the new heated tobacco platform.
An experimental method to study emissions from heated tobacco between 100-200°C
TLDR
A bench-top tube furnace is designed and systematically studied the effects of heating temperatures on selected gas phase and aerosol phase compounds using an ISO machine-smoking protocol to demonstrate the practical utility of this tool to study low-temperature toxicant formation and emission from heated tobacco.
Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe−/− Mice—An Integrative Systems Toxicology Analysis
  • B. Titz, S. Boué, J. Hoeng
  • Biology
    Toxicological sciences : an official journal of the Society of Toxicology
  • 2016
TLDR
The complex biological response of the lungs to CS exposure is demonstrated and the benefits of cessation or switching to a heat-not-burn product using a design such as those employed in this study are supported.
Eclipse: does it live up to its health claims?
TLDR
Eclipse appears to be at least as toxic as some commercially available cigarette brands and consumers may be misled by RJR's health claims into believing that Eclipse is a safer alternative to conventional cigarettes, underscoring the need for regulatory intervention.
How to define e-cigarette prevalence? Finding clues in the use frequency distribution
TLDR
Investigating the number of days out of the past 30 days when adults had used e-cigarettes to understand patterns of use found infrequent users were more likely to cite curiosity and less likely to citing quitting/cutting down other tobacco use as reasons for use.
Risk Factors for Exclusive E-Cigarette Use and Dual E-Cigarette Use and Tobacco Use in Adolescents
TLDR
A US adolescent sample with one of the largest prevalence rates of e-cigarette only use and dual use in the existing literature raises the possibility that e-cigarettes are recruiting medium-risk adolescents, who otherwise would be less susceptible to tobacco product use.
e-Cigarette awareness, use, and harm perceptions in US adults.
TLDR
In both surveys, non-Hispanic Whites, current smokers, young adults, and those with at least a high-school diploma were most likely to perceive e-cigarettes as less harmful than regular cigarettes.
E-cigarette sales rapidly lose steam
  • The Wall Street Journal
  • 2015
...
...