Induction of xenobiotic metabolising enzymes in the common brushtail possum, Trichosurus vulpecula, by Eucalyptus terpenes.

@article{Pass1999InductionOX,
  title={Induction of xenobiotic metabolising enzymes in the common brushtail possum, Trichosurus vulpecula, by Eucalyptus terpenes.},
  author={Georgia J. Pass and Stuart McLean and Ieva Stupans},
  journal={Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology},
  year={1999},
  volume={124 3},
  pages={239-46}
}
The mixed function oxidase (MFO) activity and content was studied in the liver of common brushtail possums fed for 10 days on a diet containing a mixture of terpenes found in Eucalyptus leaves on which possums commonly browse. The MFOs were compared to the MFOs in possums fed a control diet of fruits and cereals only. The terpenes chosen were 1,8-cineole, p-cymene, alpha-pinene and limonene. The selected terpenes caused induction of P450 enzymes, as shown by a 53% higher cytochrome P450 content… CONTINUE READING

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References

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Showing 1-10 of 44 references

Mixed function oxidases in an Australian marsupial, the brushtail possum (Trichosurus vulpecula).

Archives of environmental contamination and toxicology • 1997
View 5 Excerpts
Highly Influenced

Cytochrome P450 enzyme activities in the Australian brushtail possum, Trichosurus 6ulpec- G.J

A Olkowski, R Gooneratne, C. Eason
Pass et al. / Comparati6e Biochemistry and Physiology, Part C • 1999
View 1 Excerpt

Hepatic microsomal enzyme activity in the koala and tammar wallaby: high 17beta-hydroxysteroid oxidoreductase activity in koala liver microsomes.

Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology • 1999
View 1 Excerpt

In vitro hepatic metabolism of CYP3A-mediated drugs quinine and midazolam in the common brushtail possum (Trichosurus 6ulpecula)

P-C Ho, X-X Luo, JS Macauley, RG Murray, S. Wanwimolruk
Environ Toxicol Chem • 1998
View 1 Excerpt

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