Induction of tyrosine aminotransferase and amino acid transport in rat hepatoma cells by insulin and the insulin-like growth factor, multiplication-stimulating activity. Mediation by insulin and multiplication-stimulating activity receptors.

Abstract

Insulin stimulates a 2-fold increase in the amount of tyrosine aminotransferase and a 5-10-fold increase in the rate of amino acid transport in dexamethasone-treated rat hepatoma cells. In order to determine whether these effects are mediated by insulin receptors or receptors for insulin-like growth factors, we have examined the binding of 125I-labeled… (More)

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@article{Heaton1980InductionOT, title={Induction of tyrosine aminotransferase and amino acid transport in rat hepatoma cells by insulin and the insulin-like growth factor, multiplication-stimulating activity. Mediation by insulin and multiplication-stimulating activity receptors.}, author={Joanne H. Heaton and Edward E. Schilling and Thomas D. Gelehrter and Matthew M Rechler and Carrie Spencer and S. Peter Nissley}, journal={Biochimica et biophysica acta}, year={1980}, volume={632 2}, pages={192-203} }