Induction of type C viruses in cultured guinea pig cells.

  title={Induction of type C viruses in cultured guinea pig cells.},
  author={Debi P. Nayak and Patrick R. Murray},
  journal={Journal of virology},
  volume={12 1},
Particles morphologically resembling type C viruses were activated by bromodeoxyuridine (BUdR; 10(-4) M) treatment of cultured guinea pig cells. Virus particles were isolated from the cells of normal and leukemic strain 2 and random-bred guinea pigs (adult and embryonic). Immature virus particles with electron-lucent cores were found in the cytoplasmic matrix. The mature particles with electron-dense cores were found outside the cells and some appeared in the process of budding from the plasma… CONTINUE READING
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