Induction of tolerance to ischemia: alterations in second-messenger systems in the gerbil hippocampus.


Preconditioning the brain with sublethal ischemia protects against neuronal damage following subsequent ischemic insult. Using [3H]inositol 1,4,5-triphosphate (IP3), [3H]phorbol 12,13-dibutyrate (PDBu), [3H]cyclic adenosine monophosphate (cAMP) and [3H]rolipram, we performed quantitative autoradiography to determine postischemic alterations in second… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.