Induction of the neural crest state: control of stem cell attributes by gene regulatory, post-transcriptional and epigenetic interactions.

@article{Prasad2012InductionOT,
  title={Induction of the neural crest state: control of stem cell attributes by gene regulatory, post-transcriptional and epigenetic interactions.},
  author={M. Santha Lakshmi Prasad and Tatjana Sauka-Spengler and Carole LaBonne},
  journal={Developmental biology},
  year={2012},
  volume={366 1},
  pages={10-21}
}
Neural crest cells are a population of multipotent stem cell-like progenitors that arise at the neural plate border in vertebrates, migrate extensively, and give rise to diverse derivatives such as melanocytes, craniofacial cartilage and bone, smooth muscle, peripheral and enteric neurons and glia. The neural crest gene regulatory network (NC-GRN) includes a number of key factors that are used reiteratively to control multiple steps in the development of neural crest cells, including the… CONTINUE READING
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