Induction of the metabolism of etizolam by carbamazepine in humans

@article{Kondo2005InductionOT,
  title={Induction of the metabolism of etizolam by carbamazepine in humans},
  author={S Kondo and Takashi Fukasawa and Norio Yasui-Furukori and Toshiaki Aoshima and Akihito Suzuki and Yasunori Inoue and Tomonori Tateishi and Koichi Otani},
  journal={European Journal of Clinical Pharmacology},
  year={2005},
  volume={61},
  pages={185-188}
}
ObjectiveTo examine the effect of carbamazepine on the single oral dose pharmacokinetics of etizolam.MethodsEleven healthy male volunteers received carbamazepine 200 mg/day or placebo for 6 days in a double-blind, randomized, crossover manner, and on the sixth day they received a single oral 1-mg dose of etizolam. Blood samplings and evaluation of psychomotor function by the Digit Symbol Substitution Test and Stanford Sleepiness Scale were conducted up to 24 h after etizolam dosing. Plasma… Expand

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