Induction of the intrinsic apoptotic pathway in cells infected with cytopathic bovine virus diarrhoea virus.

@article{Grummer2002InductionOT,
  title={Induction of the intrinsic apoptotic pathway in cells infected with cytopathic bovine virus diarrhoea virus.},
  author={Beatrice Grummer and Stefanie Bendfeldt and Bettina Wagner and Irene Greiser-Wilke},
  journal={Virus research},
  year={2002},
  volume={90 1-2},
  pages={143-53}
}
Cytopathic bovine viral diarrhoea virus (cp BVDV) induces apoptosis in bovine cell cultures. This also seems to be a prominent feature in the pathogenesis of mucosal disease. To gain an insight into the molecular pathways of the cell alterations, the involvement of different members of the apoptotic cascade was analyzed. It was shown that inhibition of the mitochondrial permeability transition pore significantly delayed the cytopathic effect without affecting virus replication. Moreover, the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…