Induction of the fundic mucosa-specific glycolipid with dimethylformamide in gastric-cancer cell lines.

@article{Dohi1993InductionOT,
  title={Induction of the fundic mucosa-specific glycolipid with dimethylformamide in gastric-cancer cell lines.},
  author={Taeko Dohi and Masato Nakasuji and Masamitsu Oshima},
  journal={International journal of cancer},
  year={1993},
  volume={53 1},
  pages={137-40}
}
We have previously reported that a glycolipid GalNAc beta 1-4[NeuAc alpha 2-3]Gal beta 1-4GlcNAc beta 1-3Gal beta 1-4Glc-Cer named NGM-1 is present specifically in the human gastric fundic mucosa, but not in other organs. In gastric-cancer tissue and cancer cell lines, this glycolipid completely disappears. These findings imply that NGM-1 is expressed only… CONTINUE READING