Induction of tenascin in rat arterial injury. Relationship to altered smooth muscle cell phenotype.

@article{Hedin1991InductionOT,
  title={Induction of tenascin in rat arterial injury. Relationship to altered smooth muscle cell phenotype.},
  author={Ulf Hedin and Jan Arne Holm and G{\"o}ran K. Hansson},
  journal={The American journal of pathology},
  year={1991},
  volume={139 3},
  pages={649-56}
}
Arterial smooth muscle cells produce large amounts of extracellular matrix molecules during repair processes and in primary culture. This occurs after a transition of the cells from a contractile to a synthetic phenotype and together with the acquisition of proliferative capacity. Here, the deposition of the glycoprotein tenascin in the extracellular matrix of rat arterial smooth muscle cells in vivo and in vitro was studied by immunofluorescence microscopy and immunoblotting. Tenascin was… CONTINUE READING

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