Induction of synaptic potentiation in hippocampus by patterned stimulation involves two events.

@article{Larson1986InductionOS,
  title={Induction of synaptic potentiation in hippocampus by patterned stimulation involves two events.},
  author={Jennifer Larson and Gary Lynch},
  journal={Science},
  year={1986},
  volume={232 4753},
  pages={985-8}
}
Electrical stimulation of axons in the hippocampus with short high-frequency bursts that resemble in vivo activity patterns produces stable potentiation of postsynaptic responses when the bursts occur at intervals of 200 milliseconds but not 2 seconds. When a burst was applied to one input and a second burst applied to a different input to the same target neuron 200 milliseconds later, only the synapses activated by the second burst showed stable potentiation. This effect was observed even when… CONTINUE READING
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