Induction of specific transcription by RNA polymerase III in transformed cells.

@article{Carey1986InductionOS,
  title={Induction of specific transcription by RNA polymerase III in transformed cells.},
  author={Michael F Carey and Karambir Singh and Michael R Botchan and Nicholas R. Cozzarelli},
  journal={Molecular and cellular biology},
  year={1986},
  volume={6 9},
  pages={3068-76}
}
RNA polymerase III (pol III) transcripts of the highly repeated mouse B2 gene family are increased in many oncogenically transformed murine cell lines. In cells transformed by simian virus 40, the small, cytoplasmic B2 RNAs are present at 20-fold-higher levels than in normal cells (M. R. D. Scott, K. Westphal, and P. W. J. Rigby, Cell 34:557-567, 1983; K. Singh, M. Carey, S. Saragosti, and M. Botchan, Nature [London] 314:553-556). We found that transcripts of the highly repeated B1 gene family… CONTINUE READING

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