Induction of protective immunity to Haemophilus ducreyi in the temperature-dependent rabbit model of experimental chancroid.

@article{Hansen1994InductionOP,
  title={Induction of protective immunity to Haemophilus ducreyi in the temperature-dependent rabbit model of experimental chancroid.},
  author={Eric J. Hansen and Sheryl R. Lumbley and J. A. Richardson and Bret K Purcell and Megan K Stevens and Leslie D Cope and Jacques Yao Datt{\'e} and Justin D. Radolf},
  journal={Journal of immunology},
  year={1994},
  volume={152 1},
  pages={184-92}
}
The temperature-dependent rabbit model for chancroid, a sexually transmitted disease caused by the fastidious Gram-negative bacterium Haemophilus ducreyi, was used to investigate the abilities of previous infection and immunization with an acellular preparation of H. ducreyi to induce protective immunity. In the first set of experiments, animals were infected intradermally with either the 35000 or Cha-1 strains of H. ducreyi and then rechallenged 30 days later with both the homologous and… CONTINUE READING

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