Induction of proline-rich proteins in hamster salivary glands by isoproterenol treatment and an unusual growth inhibition by tannins.

@article{Mehansho1987InductionOP,
  title={Induction of proline-rich proteins in hamster salivary glands by isoproterenol treatment and an unusual growth inhibition by tannins.},
  author={Haile Mehansho and David Kong Ann and Larry G. Butler and J. C. Rogler and Don M. Carlson},
  journal={The Journal of biological chemistry},
  year={1987},
  volume={262 25},
  pages={12344-50}
}
Treatment of hamsters with the beta-agonist isoproterenol caused a dramatic increase in a series of unusual proteins in the parotid and submandibular glands. These proteins are acid soluble and they contain high amounts (mol%) of glutamate plus glutamine (30-35), proline (23-30), and glycine (12-25). Three proteins (HP45, HP43a, and HP43b) were isolated from trichloroacetic acid extracts of parotid glands of isoproterenol-treated hamsters. The basic protein (HP45) was not retained by DEAE… CONTINUE READING

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