Induction of ovulation and superovulation in mares using equine LH and FSH separated by hydrophobic interaction chromatography.

@article{Hofferer1993InductionOO,
  title={Induction of ovulation and superovulation in mares using equine LH and FSH separated by hydrophobic interaction chromatography.},
  author={S. Hofferer and François Lecompte and Thierry Magallon and Elizabeth Palmer and Yves Combarnous},
  journal={Journal of reproduction and fertility},
  year={1993},
  volume={98 2},
  pages={
          597-602
        }
}
Pharmacological control of reproduction in mares requires the use of equine gonadotrophins to avoid induced immunological resistance. Crude equine gonadotrophins (CEG) have been used but the presence of equine luteinizing hormone (eLH) and follicle-stimulating hormone (eFSH) in CEG has led to disappointing results in superovulation studies. Separation of eLH and eFSH activities from CEG is necessary to overcome this problem. The hydrophobic properties of the two hormones were sufficiently… CONTINUE READING

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