Induction of neurite outgrowth by a conditioned-medium factor bound to the culture substratum.

@article{Collins1978InductionON,
  title={Induction of neurite outgrowth by a conditioned-medium factor bound to the culture substratum.},
  author={Ft. Collins},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1978},
  volume={75 10},
  pages={5210-3}
}
  • Ft. Collins
  • Published 1978 in
    Proceedings of the National Academy of Sciences…
Heart-cell conditioned medium (HCM) induces rapid neurite outgrowth from isolated neurons in culture. The following evidence indicates that this action of HCM is due to a trypsin-sensitive factor which attaches to the polyornithinecoated culture substratum: (i) Pretreatment of the culture substratum with HCM allows rapid neurite outgrowth to occur even in… CONTINUE READING