Induction of neural-like differentiation in human mesenchymal stem cells derived from bone marrow, fat, spleen and thymus.

@article{Krampera2007InductionON,
  title={Induction of neural-like differentiation in human mesenchymal stem cells derived from bone marrow, fat, spleen and thymus.},
  author={Mauro Krampera and Silvia Marconi and Annalisa Pasini and Mirco Gali{\'e} and Gino Rigotti and Federico Mosna and Martina Tinelli and Laura L. Lovato and Elena Anghileri and Angelo Andreini and Giovanni Pizzolo and Andrea Sbarbati and Bruno Bonetti},
  journal={Bone},
  year={2007},
  volume={40 2},
  pages={382-90}
}
Mesenchymal stem cells (MSCs) from bone marrow (BM) and sub-cutaneous fat are known to differentiate into neural cells under appropriate stimuli. We describe here the neural-like differentiation of human MSCs obtained from spleen and thymus, induced either with chemical factors or with co-culture with human Schwann cells (Sc). Under the effect of neural differentiation medium, most MSCs from BM, fat, spleen and thymus acquired morphological changes suggestive of cells of astrocytic/neuronal and… CONTINUE READING
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