Induction of muscle pioneers and floor plate is distinguished by the zebrafish no tail mutation

@article{Halpern1993InductionOM,
  title={Induction of muscle pioneers and floor plate is distinguished by the zebrafish no tail mutation},
  author={M. Halpern and R. Ho and C. Walker and C. Kimmel},
  journal={Cell},
  year={1993},
  volume={75},
  pages={99-111}
}
Dorsal mesoderm is thought to provide important signals for axis formation and neural differentiation in vertebrate embryos. We have examined induction and patterning in a zebrafish mutant, no tail, that lacks a derivative of dorsal mesoderm, the notochord. Despite the absence of a differentiated notochord, development of the central nervous system including floor plate appears normal, likely owing to the presence of notochord precursor cells. In contrast, somites are misshapen, and muscle… Expand
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