Induction of mucosal antibody responses by microsphere-encapsulated formalin-inactivated simian immunodeficiency virus in a male urethral challenge model.

Abstract

Male rhesus macaques were immunized mucosally with microsphere-encapsulated formalin-inactivated simian immunodeficiency virus (SIV) particles in a test of immunogenicity and protection against mucosal SIV challenge. Tracheal boosting of animals that had been primed intramuscularly resulted in strong serum ELISA titers to SIV, and evidence of local IgA… (More)

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Cite this paper

@article{Ishizaka1999InductionOM, title={Induction of mucosal antibody responses by microsphere-encapsulated formalin-inactivated simian immunodeficiency virus in a male urethral challenge model.}, author={Sally T. Ishizaka and Zimra R Israel and Agegnehu Gettie and Eric M. Mishkin and Jay K Staas and Richard M. Gilley and Peter J. Dailey and D. C. Montefiori and Preston A. Marx and John H. Eldridge}, journal={Vaccine}, year={1999}, volume={17 22}, pages={2817-25} }