Induction of mouse erythroleukemia cells by microinjection of inducing compound.

@article{Diacumakos1981InductionOM,
  title={Induction of mouse erythroleukemia cells by microinjection of inducing compound.},
  author={Elaine G. Diacumakos and Lillian Killos and Lingaku Lee and Wayne F Anderson},
  journal={Experimental cell research},
  year={1981},
  volume={131 1},
  pages={
          73-7
        }
}
Abstract Physical microinjection is shown to be a useful procedure for inserting biologically active molecules into mammalian cells. Mouse erythroleukemia cells have been attached to a coverslip, microinjected with the inducer hexamethylene-bisacetamide (HMBA) and incubated for 5–6 days in the absence of inducer. The injected cells appear to undergo normal differentiation and synthesize hemoglobin. This is the first example of a cell being activated to undergo differentiation by direct… CONTINUE READING