Induction of mixed chimerism using combinatory cell-based immune modulation with mesenchymal stem cells and regulatory T cells for solid-organ transplant tolerance.

Abstract

Establishment of mixed chimerism is an ideal approach to induce donor-specific tolerance while expanding its potential in various clinical settings. Despite the developments in partial conditioning regimens, improvements are still needed in reducing toxicity and bone marrow transplantation-related complications. Recently, cell-based therapies, including… (More)
DOI: 10.1089/scd.2013.0617

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Cite this paper

@article{Im2014InductionOM, title={Induction of mixed chimerism using combinatory cell-based immune modulation with mesenchymal stem cells and regulatory T cells for solid-organ transplant tolerance.}, author={Keon-Il Im and Min-Jung Park and Nayoun Kim and Jung-Yeon Lim and Hyun-Sil Park and Sung-Hee Lee and Young-Sun Nam and Eun-Sol Lee and Jung-Ho Lee and Mi-la Cho and Seok-Goo Cho}, journal={Stem cells and development}, year={2014}, volume={23 19}, pages={2364-76} }