Induction of micronuclei by Zearalenone in Vero monkey kidney cells and in bone marrow cells of mice: protective effect of Vitamin E.

@article{Ouanes2003InductionOM,
  title={Induction of micronuclei by Zearalenone in Vero monkey kidney cells and in bone marrow cells of mice: protective effect of Vitamin E.},
  author={Zouhour Ouanes and Salwa Ben Abid and Imen Ben Ayed and Rachid Anane and Th{\'e}ophile Amondo Mobio and Edmond Eku{\'e} Creppy and Hassen Bacha},
  journal={Mutation research},
  year={2003},
  volume={538 1-2},
  pages={63-70}
}
Zearalenone (ZEN) is a non-steroidal estrogenic mycotoxin mainly produced by Fusarium graminaerum, found as a world-wide contaminant mainly of corn and wheat. Previous studies have demonstrated that among several other effects on animals and humans, ZEN also displays hepatotoxicity, immunotoxicity and nephrotoxicity. ZEN is mainly known as a hormonal disrupter due to its estrogenic activities and consequent toxicity for reproduction. Furthermore, mutagenic and genotoxic proprieties of ZEN were… CONTINUE READING
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